Melanie Schulz: Skin Rejuvenation with Q‐switched Fractional 1064nm and 532nm
532 nm and 1064 nm Q-switched laser pulses are known to improve the appearance of wrinkles and remove signs of photoaged skin. The rapid vaporization and thermal expansion stresses, leading to photomechanical skin damage, have been used successfully to date for the correction of exogenous and endogenous deep pigmentation.
In this comparative, single blind, randomized, un-controlled study looking at 1064 nm and 532 nm fractional Q-switched laser treatment, the effects on rejuvenation and pigment reduction in 2 cohorts of laser-naïve volunteers were studied.
Subjects (30-60 years, Fitzpatrick type II to IV with signs of ageing, but otherwise with healthy skin, were randomized into 1 of 2 groups (n=5/group) for either 1064 nm or 532 nm treatments. Each volunteer had 3 treatments in total spaced out by 2-4 weeks, with a final follow-up 2 months after the last treatment. In both cohorts, improvement was observed after each treatment for skin rejuvenation and pigment reduction with both 1064 nm and 532 nm Q-switched fractional laser.
A further cross-over study is required to examine the effects of combining both 1064 nm and 532 nm. Initial results have shown positive outcomes.
